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The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia

Cystic fibrosis (CF) patients are extremely vulnerable to Burkholderia cepacia complex (Bcc) infections. However, the underlying etiology is poorly understood. We tested the hypothesis that short palate lung and nasal epithelial clone 1 (SPLUNC1)–epithelial sodium channel (ENaC) interactions at the...

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Publicado en:Respir Res
Main Authors: Ahmad, Saira, Kim, Christine Seul Ki, Tarran, Robert
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368771/
https://ncbi.nlm.nih.gov/pubmed/32680508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01454-5
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