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SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage
Many epithelia, including the superficial epithelia of the airways, are thought to secrete “volume sensors,” which regulate the volume of the mucosal lining fluid. The epithelial Na(+) channel (ENaC) is often the rate limiting factor in fluid absorption, and must be cleaved by extracellular and/or i...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708735/ https://ncbi.nlm.nih.gov/pubmed/19541605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903609106 |
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