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The N terminus of α-ENaC mediates ENaC cleavage and activation by furin

Epithelial Na(+) channels comprise three homologous subunits (α, β, and γ) that are regulated by alternative splicing and proteolytic cleavage. Here, we determine the basis of the reduced Na(+) current (I(Na)) that results from expression of a previously identified, naturally occurring splice varian...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Gen Physiol
Egile Nagusiak: Kota, Pradeep, Gentzsch, Martina, Dang, Yan L., Boucher, Richard C., Stutts, M. Jackson
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080898/
https://ncbi.nlm.nih.gov/pubmed/29980634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711860
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