Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer

BACKGROUND: Radiation therapy (RT) has the potential to enhance the efficacy of immunotherapy, such as checkpoint inhibitors, which has dramatically altered the landscape of treatments for many cancers, but not yet for pancreatic ductal adenocarcinoma (PDAC). Our prior studies demonstrated that PD l...

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Dettagli Bibliografici
Pubblicato in:J Immunother Cancer
Autori principali: Fujiwara, Kenji, Saung, May Tun, Jing, Hao, Herbst, Brian, Zarecki, MacKenzie, Muth, Stephen, Wu, Annie, Bigelow, Elaine, Chen, Linda, Li, Keyu, Jurcak, Neolle, Blair, Alex B, Ding, Ding, Wichroski, Michael, Blum, Jordan, Cheadle, Nathan, Koenitzer, Jennifer, Zheng, Lei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2020
Soggetti:
Basic Tumor Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368549/
https://ncbi.nlm.nih.gov/pubmed/32675194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000351
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