Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer

BACKGROUND: Radiation therapy (RT) has the potential to enhance the efficacy of immunotherapy, such as checkpoint inhibitors, which has dramatically altered the landscape of treatments for many cancers, but not yet for pancreatic ductal adenocarcinoma (PDAC). Our prior studies demonstrated that PD l...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Immunother Cancer
المؤلفون الرئيسيون: Fujiwara, Kenji, Saung, May Tun, Jing, Hao, Herbst, Brian, Zarecki, MacKenzie, Muth, Stephen, Wu, Annie, Bigelow, Elaine, Chen, Linda, Li, Keyu, Jurcak, Neolle, Blair, Alex B, Ding, Ding, Wichroski, Michael, Blum, Jordan, Cheadle, Nathan, Koenitzer, Jennifer, Zheng, Lei
التنسيق: Artigo
اللغة:Inglês
منشور في: BMJ Publishing Group 2020
الموضوعات:
Basic Tumor Immunology
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368549/
https://ncbi.nlm.nih.gov/pubmed/32675194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000351
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