Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer

BACKGROUND: Radiation therapy (RT) has the potential to enhance the efficacy of immunotherapy, such as checkpoint inhibitors, which has dramatically altered the landscape of treatments for many cancers, but not yet for pancreatic ductal adenocarcinoma (PDAC). Our prior studies demonstrated that PD l...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Fujiwara, Kenji, Saung, May Tun, Jing, Hao, Herbst, Brian, Zarecki, MacKenzie, Muth, Stephen, Wu, Annie, Bigelow, Elaine, Chen, Linda, Li, Keyu, Jurcak, Neolle, Blair, Alex B, Ding, Ding, Wichroski, Michael, Blum, Jordan, Cheadle, Nathan, Koenitzer, Jennifer, Zheng, Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Basic Tumor Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368549/
https://ncbi.nlm.nih.gov/pubmed/32675194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000351
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