Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer

BACKGROUND: Radiation therapy (RT) has the potential to enhance the efficacy of immunotherapy, such as checkpoint inhibitors, which has dramatically altered the landscape of treatments for many cancers, but not yet for pancreatic ductal adenocarcinoma (PDAC). Our prior studies demonstrated that PD l...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Fujiwara, Kenji, Saung, May Tun, Jing, Hao, Herbst, Brian, Zarecki, MacKenzie, Muth, Stephen, Wu, Annie, Bigelow, Elaine, Chen, Linda, Li, Keyu, Jurcak, Neolle, Blair, Alex B, Ding, Ding, Wichroski, Michael, Blum, Jordan, Cheadle, Nathan, Koenitzer, Jennifer, Zheng, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368549/
https://ncbi.nlm.nih.gov/pubmed/32675194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000351
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