MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

TRIM family proteins play integral roles in the innate immune response to virus infection. MG53 (TRIM72) is essential for cell membrane repair and is believed to be a muscle-specific TRIM protein. Here we show human macrophages express MG53, and MG53 protein expression is reduced following virus inf...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Sermersheim, Matthew, Kenney, Adam D., Lin, Pei-Hui, McMichael, Temet M., Cai, Chuanxi, Gumpper, Kristyn, Adesanya, T. M. Ayodele, Li, Haichang, Zhou, Xinyu, Park, Ki-Ho, Yount, Jacob S., Ma, Jianjie
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368064/
https://ncbi.nlm.nih.gov/pubmed/32681036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17177-6
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