MG53 Protein Protects Aortic Valve Interstitial Cells From Membrane Injury and Fibrocalcific Remodeling

BACKGROUND: The aortic valve of the heart experiences constant mechanical stress under physiological conditions. Maladaptive valve injury responses contribute to the development of valvular heart disease. Here, we test the hypothesis that MG53 (mitsugumin 53), an essential cell membrane repair prote...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Adesanya, T. M. Ayodele, Russell, Melanie, Park, Ki Ho, Zhou, Xinyu, Sermersheim, Matthew A., Gumpper, Kristyn, Koenig, Sara N., Tan, Tao, Whitson, Bryan A., Janssen, Paul M. L., Lincoln, Joy, Zhu, Hua, Ma, Jianjie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405656/
https://ncbi.nlm.nih.gov/pubmed/30741589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009960
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