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Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes

Bunyavirales is an order of segmented negative-strand RNA viruses comprising several life-threatening pathogens against which no effective treatment is currently available. Replication and transcription of the RNA genome constitute essential processes performed by the virally encoded multi-domain RN...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Arragain, Benoît, Effantin, Grégory, Gerlach, Piotr, Reguera, Juan, Schoehn, Guy, Cusack, Stephen, Malet, Hélène
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368059/
https://ncbi.nlm.nih.gov/pubmed/32681014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17349-4
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