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Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter
Segmented negative-strand RNA virus (sNSV) polymerases transcribe and replicate the viral RNA (vRNA) within a ribonucleoprotein particle (RNP). We present cryo-EM and X-ray structures of, respectively, apo- and vRNA bound La Crosse orthobunyavirus (LACV) polymerase that give atomic-resolution insigh...
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| 發表在: | Cell |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cell Press
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4459711/ https://ncbi.nlm.nih.gov/pubmed/26004069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.006 |
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