Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A

The phosphatases PP1 and PP2A are responsible for the majority of dephosphorylation reactions on phosphoserine (pSer) and phosphothreonine (pThr), and are involved in virtually all cellular processes and numerous diseases. The catalytic subunits exist in cells in form of holoenzymes, which impart su...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Hoermann, Bernhard, Kokot, Thomas, Helm, Dominic, Heinzlmeir, Stephanie, Chojnacki, Jeremy E., Schubert, Thomas, Ludwig, Christina, Berteotti, Anna, Kurzawa, Nils, Kuster, Bernhard, Savitski, Mikhail M., Köhn, Maja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367873/
https://ncbi.nlm.nih.gov/pubmed/32681005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17334-x
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