Structural basis for the interaction of human herpesvirus 6B tetrameric glycoprotein complex with the cellular receptor, human CD134

A unique glycoprotein is expressed on the virus envelope of human herpesvirus 6B (HHV-6B): the complex gH/gL/gQ1/gQ2 (hereafter referred to as the HHV-6B tetramer). This tetramer recognizes a host receptor expressed on activated T cells: human CD134 (hCD134). This interaction is essential for HHV-6B...

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Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Nishimura, Mitsuhiro, Novita, Bernadette Dian, Kato, Takayuki, Handayani Tjan, Lidya, Wang, Bochao, Wakata, Aika, Lystia Poetranto, Anna, Kawabata, Akiko, Tang, Huamin, Aoshi, Taiki, Mori, Yasuko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367449/
https://ncbi.nlm.nih.gov/pubmed/32678833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008648
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