Tetrameric glycoprotein complex gH/gL/gQ1/gQ2 is a promising vaccine candidate for human herpesvirus 6B

Primary infection of human herpesvirus 6B (HHV-6B) occurs in infants after the decline of maternal immunity and causes exanthema subitum accompanied by a high fever, and it occasionally develops into encephalitis resulting in neurological sequelae. There is no effective prophylaxis for HHV-6B, and i...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Wang, Bochao, Hara, Kouichi, Kawabata, Akiko, Nishimura, Mitsuhiro, Wakata, Aika, Tjan, Lidya Handayani, Poetranto, Anna Lystia, Yamamoto, Chisato, Haseda, Yasunari, Aoshi, Taiki, Munakata, Lisa, Suzuki, Ryo, Komatsu, Masato, Tsukamoto, Ryuko, Itoh, Tomoo, Nishigori, Chikako, Saito, Yasuyuki, Matozaki, Takashi, Mori, Yasuko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377363/
https://ncbi.nlm.nih.gov/pubmed/32702057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008609
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