The Combination of gQ1 and gQ2 in Human Herpesvirus 6A and 6B Regulates the Viral Tetramer Function for Their Receptor Recognition

Human herpesvirus 6A (HHV-6A) and HHV-6B use different cellular receptors, human CD46 and CD134, respectively, and have different cell tropisms, although they have 90% similarity at the nucleotide level. An important feature that characterizes HHV-6A/6B is the glycoprotein H (gH)/gL/gQ1/gQ2 complex...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Wakata, Aika, Tjan, Lidya Handayani, Nishimura, Mitsuhiro, Kawabata, Akiko, Poetranto, Anna Lystia, Yamamoto, Chisato, Arii, Jun, Mori, Yasuko
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2021
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092820/
https://ncbi.nlm.nih.gov/pubmed/33298543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01638-20
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