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Human Herpesvirus 6 Glycoprotein Complex Formation Is Required for Folding and Trafficking of the gH/gL/gQ1/gQ2 Complex and Its Cellular Receptor Binding

Human herpesvirus 6 (HHV-6) is a T-cell-tropic betaherpesvirus. A glycoprotein (g) complex that is unique to HHV-6, gH/gL/gQ1/gQ2, is a viral ligand for its cellular receptor, human CD46. However, whether complex formation or one component of the complex is required for CD46 binding and how the comp...

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Detalhes bibliográficos
Main Authors: Tang, Huamin, Hayashi, Mayuko, Maeki, Takahiro, Yamanishi, Koichi, Mori, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194968/
https://ncbi.nlm.nih.gov/pubmed/21849437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05251-11
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