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Determinants of Human CD134 Essential for Entry of Human Herpesvirus 6B

We identified two key amino acid residues within human CD134 (hCD134) that are required for its interaction with human herpesvirus 6B (HHV-6B) and for HHV-6B entry into cells. One of the residues (K79) allows access of the HHV-6B ligand to hCD134. Murine CD134 (mCD134) functioned as an HHV-6B recept...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Tang, Huamin, Mori, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577881/
https://ncbi.nlm.nih.gov/pubmed/26202244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01606-15
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