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Negative feedback regulation by HuR controls TRIM21 expression and function in response to UV radiation
The E3 ubiquitin ligase TRIM21 plays a crucial role as a negative regulator of innate immune responses. Recent evidence has also indicated the involvement of TRIM21 in the genotoxic stress response and suppressing tumorigenesis. Our previous work has demonstrated a new function of TRIM21 in inhibiti...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7367240/ https://ncbi.nlm.nih.gov/pubmed/32678213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68646-3 |
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