Cdk9 and H2Bub1 signal to Clr6-CII/Rpd3S to suppress aberrant antisense transcription

Mono-ubiquitylation of histone H2B (H2Bub1) and phosphorylation of elongation factor Spt5 by cyclin-dependent kinase 9 (Cdk9) occur during transcription by RNA polymerase II (RNAPII), and are mutually dependent in fission yeast. It remained unclear whether Cdk9 and H2Bub1 cooperate to regulate the e...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Sansó, Miriam, Parua, Pabitra K, Pinto, Daniel, Svensson, J Peter, Pagé, Viviane, Bitton, Danny A, MacKinnon, Sarah, Garcia, Patricia, Hidalgo, Elena, Bähler, Jürg, Tanny, Jason C, Fisher, Robert P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367204/
https://ncbi.nlm.nih.gov/pubmed/32496538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa474
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