Argonaute binding within 3′-untranslated regions poorly predicts gene repression

Despite two decades of study, the full scope of RNAi in mammalian cells has remained obscure. Here we combine: (i) Knockout of argonaute (AGO) variants; (ii) RNA sequencing analysis of gene expression changes and (iii) Enhanced Crosslinking Immunoprecipitation Sequencing (eCLIP-seq) using anti-AGO2...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Chu, Yongjun, Kilikevicius, Audrius, Liu, Jing, Johnson, Krystal C, Yokota, Shinnichi, Corey, David R
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
RNA and RNA-protein complexes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367155/
https://ncbi.nlm.nih.gov/pubmed/32501500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa478
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker