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Preferential microRNA targeting revealed by in vivo competitive binding and differential Argonaute immunoprecipitation

MicroRNAs (miRNAs) have been described to simultaneously inhibit hundreds of targets, albeit to a modest extent. It was recently proposed that there could exist more specific, exceptionally strong binding to a subgroup of targets. However, it is unknown, whether this is the case and how such targets...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Werfel, Stanislas, Leierseder, Simon, Ruprecht, Benjamin, Kuster, Bernhard, Engelhardt, Stefan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622317/
https://ncbi.nlm.nih.gov/pubmed/28973447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx640
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