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Dual SMAD inhibition and Wnt inhibition enable efficient and reproducible differentiations of induced pluripotent stem cells into retinal ganglion cells

Glaucoma is a group of progressive optic neuropathies that share common biological and clinical characteristics including irreversible changes to the optic nerve and visual field loss caused by the death of retinal ganglion cells (RGCs). The loss of RGCs manifests as characteristic cupping or optic...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Chavali, Venkata R. M., Haider, Naqi, Rathi, Sonika, Vrathasha, Vrathasha, Alapati, Teja, He, Jie, Gill, Kamaljot, Nikonov, Roman, Duong, Thu T., McDougald, Devin S., Nikonov, Sergei, O’Brien, Joan, Mills, Jason A.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366935/
https://ncbi.nlm.nih.gov/pubmed/32678240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68811-8
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