Dual SMAD inhibition and Wnt inhibition enable efficient and reproducible differentiations of induced pluripotent stem cells into retinal ganglion cells

Glaucoma is a group of progressive optic neuropathies that share common biological and clinical characteristics including irreversible changes to the optic nerve and visual field loss caused by the death of retinal ganglion cells (RGCs). The loss of RGCs manifests as characteristic cupping or optic...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Chavali, Venkata R. M., Haider, Naqi, Rathi, Sonika, Vrathasha, Vrathasha, Alapati, Teja, He, Jie, Gill, Kamaljot, Nikonov, Roman, Duong, Thu T., McDougald, Devin S., Nikonov, Sergei, O’Brien, Joan, Mills, Jason A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366935/
https://ncbi.nlm.nih.gov/pubmed/32678240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68811-8
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