Carregando...
SIRT1 and NRF2 Gene Transfer Mediate Distinct Neuroprotective Effects Upon Retinal Ganglion Cell Survival and Function in Experimental Optic Neuritis
PURPOSE: Optic neuritis is a condition defined by autoimmune-mediated demyelination of the optic nerve and death of retinal ganglion cells. SIRT1 and NRF2 stimulate anti-inflammatory mechanisms and have previously demonstrated therapeutic value in preclinical models of neurodegenerative disease. Her...
Na minha lista:
| Publicado no: | Invest Ophthalmol Vis Sci |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5839257/ https://ncbi.nlm.nih.gov/pubmed/29494741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22972 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|