Development of potent inhibitors of the human microsomal epoxide hydrolase

Microsomal epoxide hydrolase (mEH) hydrolyzes a wide range of epoxide containing molecules. Although involved in the metabolism of xenobiotics, recent studies associate mEH with the onset and development of certain disease conditions. This phenomenon is partially attributed to the significant role m...

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Bibliographic Details
Published in:Eur J Med Chem
Main Authors: Barnych, Bogdan, Singh, Nalin, Negrel, Sophie, Zhang, Yue, Magis, Damien, Roux, Capucine, Hua, Xiude, Ding, Zhewen, Morisseau, Christophe, Tantillo, Dean J., Siegel, Justin B., Hammock, Bruce D.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366823/
https://ncbi.nlm.nih.gov/pubmed/32203787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112206
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