Development of potent inhibitors of the human microsomal epoxide hydrolase

Microsomal epoxide hydrolase (mEH) hydrolyzes a wide range of epoxide containing molecules. Although involved in the metabolism of xenobiotics, recent studies associate mEH with the onset and development of certain disease conditions. This phenomenon is partially attributed to the significant role m...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Barnych, Bogdan, Singh, Nalin, Negrel, Sophie, Zhang, Yue, Magis, Damien, Roux, Capucine, Hua, Xiude, Ding, Zhewen, Morisseau, Christophe, Tantillo, Dean J., Siegel, Justin B., Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366823/
https://ncbi.nlm.nih.gov/pubmed/32203787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112206
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