Development of potent inhibitors of the human microsomal epoxide hydrolase

Microsomal epoxide hydrolase (mEH) hydrolyzes a wide range of epoxide containing molecules. Although involved in the metabolism of xenobiotics, recent studies associate mEH with the onset and development of certain disease conditions. This phenomenon is partially attributed to the significant role m...

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Dades bibliogràfiques
Publicat a:Eur J Med Chem
Autors principals: Barnych, Bogdan, Singh, Nalin, Negrel, Sophie, Zhang, Yue, Magis, Damien, Roux, Capucine, Hua, Xiude, Ding, Zhewen, Morisseau, Christophe, Tantillo, Dean J., Siegel, Justin B., Hammock, Bruce D.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366823/
https://ncbi.nlm.nih.gov/pubmed/32203787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112206
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