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ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating S2/S3 cleavage products of Notch
Although the physiological consequences of Notch signaling in hematopoiesis have been extensively studied, the differential effects of individual notch cleavage products remain to be elucidated. Given that ADAM10 is a critical regulator of Notch and that its deletion is embryonically lethal, we gene...
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| Gepubliceerd in: | J Immunol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7365260/ https://ncbi.nlm.nih.gov/pubmed/21368228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003318 |
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