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A Simplified Method for the Clinical-scale Generation of Central Memory-like CD8+ T Cells After Transduction With Lentiviral Vectors Encoding Antitumor Antigen T-cell Receptors

Adoptive transfer of antigen-specific CD8+ T cells can effectively treat patients with metastatic melanoma. Recent efforts have emphasized the in vitro generation of antitumor T cells by transduction of genes encoding antitumor T-cell receptors. At present, lentiviral vector-mediated transduction of...

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Bibliografske podrobnosti
izdano v:J Immunother
Main Authors: Yang, Shicheng, Dudley, Mark E., Rosenberg, Steven A., Morgan, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365020/
https://ncbi.nlm.nih.gov/pubmed/20551831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181e311cb
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