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Clinical-scale lentiviral vector transduction of PBL for TCR gene therapy and potential for expression in less differentiated cells

In human gene therapy applications, lentiviral vectors may have advantages over gamma-retroviral vectors because of their ability to transduce non-dividing cells, their resistance to gene silencing, and a lack of integration site preference. In this study, we utilized VSV-G pseudotype third generati...

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Detalhes bibliográficos
Main Authors: Yang, Shicheng, Rosenberg, Steven A., Morgan, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399689/
https://ncbi.nlm.nih.gov/pubmed/18833004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31818817c5
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