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Clinical-scale lentiviral vector transduction of PBL for TCR gene therapy and potential for expression in less differentiated cells
In human gene therapy applications, lentiviral vectors may have advantages over gamma-retroviral vectors because of their ability to transduce non-dividing cells, their resistance to gene silencing, and a lack of integration site preference. In this study, we utilized VSV-G pseudotype third generati...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399689/ https://ncbi.nlm.nih.gov/pubmed/18833004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31818817c5 |
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