Sex-dependent autosomal effects on clinical progression of Alzheimer’s disease

Sex differences in the manifestations of Alzheimer’s disease are under intense investigation. Despite the emerging importance of polygenic predictions for Alzheimer’s disease, sex-dependent polygenic effects have not been demonstrated. Here, using a sex crossover analysis, we show that sex-dependent...

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Detalhes bibliográficos
Publicado no:Brain
Principais autores: Fan, Chun Chieh, Banks, Sarah J, Thompson, Wesley K, Chen, Chi-Hua, McEvoy, Linda K, Tan, Chin Hong, Kukull, Walter, Bennett, David A, Farrer, Lindsay A, Mayeux, Richard, Schellenberg, Gerard D, Andreassen, Ole A, Desikan, Rahul, Dale, Anders M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364740/
https://ncbi.nlm.nih.gov/pubmed/32591829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa164
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