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Enrichment and Stratification for Predementia Alzheimer Disease Clinical Trials

The tau and amyloid pathobiological processes underlying Alzheimer disease (AD) progresses slowly over periods of decades before clinical manifestation as mild cognitive impairment (MCI), then more rapidly to dementia, and eventually to end-stage organ failure. The failure of clinical trials of cand...

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書誌詳細
主要な著者: Holland, Dominic, McEvoy, Linda K., Desikan, Rahul S., Dale, Anders M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474753/
https://ncbi.nlm.nih.gov/pubmed/23082203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047739
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