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Enrichment and Stratification for Predementia Alzheimer Disease Clinical Trials
The tau and amyloid pathobiological processes underlying Alzheimer disease (AD) progresses slowly over periods of decades before clinical manifestation as mild cognitive impairment (MCI), then more rapidly to dementia, and eventually to end-stage organ failure. The failure of clinical trials of cand...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474753/ https://ncbi.nlm.nih.gov/pubmed/23082203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047739 |
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