Cell type- and stimulation-dependent transcriptional programs regulated by Atg16L1 and its Crohn’s disease risk-variant T300A

Genome-wide association studies (GWAS) have identified common genetic variants impacting human diseases; however, there are indications that the functional consequences of genetic polymorphisms can be distinct depending on cell type-specific contexts, which produce divergent phenotypic outcomes. Thu...

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Publicado no:J Immunol
Main Authors: Varma, Mukund, Kadoki, Motohiko, Lefkovith, Ariel, Conway, Kara L., Gao, Kevin, Mohanan, Vishnu, Tusi, Betsabeh Khoramian, Graham, Daniel B., Latorre, Isabel J., Tolonen, Andrew C., Khor, Bernard, Ng, Aylwin C.Y., Xavier, Ramnik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364322/
https://ncbi.nlm.nih.gov/pubmed/32522834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900750
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