Muscle NAD(+) depletion and Serpina3n as molecular determinants of murine cancer cachexia—the effects of blocking myostatin and activins

OBJECTIVE: Cancer cachexia and muscle loss are associated with increased morbidity and mortality. In preclinical animal models, blocking activin receptor (ACVR) ligands has improved survival and prevented muscle wasting in cancer cachexia without an effect on tumour growth. However, the underlying m...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Metab
मुख्य लेखकों: Hulmi, J.J., Penna, F., Pöllänen, N., Nissinen, T.A., Hentilä, J., Euro, L., Lautaoja, J.H., Ballarò, R., Soliymani, R., Baumann, M., Ritvos, O., Pirinen, E., Lalowski, M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2020
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364159/
https://ncbi.nlm.nih.gov/pubmed/32599075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101046
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