Inhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during Differentiation

Phenotypes of haploid embryonic stem cells (haESCs) are dominant for recessive traits in mice. However, one major obstacle to their use is self-diploidization in daily culture. Although haESCs maintain haploidy well by deleting p53, whether they can sustain haploidy in differentiated status and the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Zhang, Wenhao, Tian, Yaru, Gao, Qian, Li, Xu, Li, Yanni, Zhang, Jinxin, Yao, Chunmeng, Wang, Yuna, Wang, Haoyu, Zhao, Yiding, Zhang, Qian, Li, Luyuan, Yu, Yang, Fan, Yong, Shuai, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363743/
https://ncbi.nlm.nih.gov/pubmed/32502463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.05.004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados