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The X to Autosome Expression Ratio in Haploid and Diploid Human Embryonic Stem Cells
Ohno proposed that the expression levels of X-linked genes have been doubled to compensate the degeneration of Y-linked homologs during the evolution of mammalian sex chromosomes, but RNA sequencing in human somatic tissues showed no such upregulation for the vast majority of X-linked genes. Here we...
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| Published in: | Mol Biol Evol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5100046/ https://ncbi.nlm.nih.gov/pubmed/27593371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw187 |
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