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Derivation of Haploid Trophoblast Stem Cells via Conversion In Vitro

Owing to their single genome, haploid cells are powerful to uncover unknown genes by performing genetic screening in mammals. However, no haploid cell line from an extraembryonic lineage has been achieved yet, which limits the application of haploid cells in placental genetic screening. Here, we sho...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Peng, Keli, Li, Xu, Wu, Congyu, Wang, Yuna, Yu, Jian, Zhang, Jinxin, Gao, Qian, Zhang, Wenhao, Zhang, Qian, Fan, Yong, Yu, Yang, Shuai, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354440/
https://ncbi.nlm.nih.gov/pubmed/30635215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.12.014
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