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Derivation and maintenance of mouse haploid embryonic stem cells

Ploidy represents the number of chromosome sets in a cell. Although gametes have a haploid genome (n), most mammalian cells have diploid genomes (2n). The diploid status of most cells correlates with the number of probable alleles for each autosomal gene and makes it difficult to target these genes...

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Détails bibliographiques
Publié dans:Nat Protoc
Auteurs principaux: Elling, Ulrich, Woods, Michael, Forment, Josep V., Fu, Beiyuan, Yang, Fengtang, Ng, Bee Ling, Vicente, Jose R., Adams, David J., Doe, Brendan, Jackson, Stephen P., Penninger, Josef M., Balmus, Gabriel
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997032/
https://ncbi.nlm.nih.gov/pubmed/31160788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0169-z
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