Derivation and maintenance of mouse haploid embryonic stem cells

Ploidy represents the number of chromosome sets in a cell. Although gametes have a haploid genome (n), most mammalian cells have diploid genomes (2n). The diploid status of most cells correlates with the number of probable alleles for each autosomal gene and makes it difficult to target these genes...

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Bibliografiske detaljer
Udgivet i:Nat Protoc
Main Authors: Elling, Ulrich, Woods, Michael, Forment, Josep V., Fu, Beiyuan, Yang, Fengtang, Ng, Bee Ling, Vicente, Jose R., Adams, David J., Doe, Brendan, Jackson, Stephen P., Penninger, Josef M., Balmus, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997032/
https://ncbi.nlm.nih.gov/pubmed/31160788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0169-z
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