Derivation and maintenance of mouse haploid embryonic stem cells

Ploidy represents the number of chromosome sets in a cell. Although gametes have a haploid genome (n), most mammalian cells have diploid genomes (2n). The diploid status of most cells correlates with the number of probable alleles for each autosomal gene and makes it difficult to target these genes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Protoc
Prif Awduron: Elling, Ulrich, Woods, Michael, Forment, Josep V., Fu, Beiyuan, Yang, Fengtang, Ng, Bee Ling, Vicente, Jose R., Adams, David J., Doe, Brendan, Jackson, Stephen P., Penninger, Josef M., Balmus, Gabriel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997032/
https://ncbi.nlm.nih.gov/pubmed/31160788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0169-z
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