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Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells

Forward genetic screens in haploid mammalian cells have recently emerged as powerful tools for the discovery and investigation of recessive traits. Use of the haploid system provides unique genetic tractability and resolution. Upon positive selection, these screens typically employ analysis of loss-...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Horn, Moritz, Kroef, Virginia, Allmeroth, Kira, Schuller, Nicole, Miethe, Stephan, Peifer, Martin, Penninger, Josef M., Elling, Ulrich, Denzel, Martin S.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839405/
https://ncbi.nlm.nih.gov/pubmed/29515774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24305
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