Perspective: Modulating the integrated stress response to slow aging and ameliorate age-related pathology

por Derisbourg, Maxime J., Hartman, Matías D., Denzel, Martin S.
Publicado en Nat Aging (2021)

Chaperoning junior faculty: Institutional support and guidance can relieve challenges for early‐career group leaders and improve academic performance

por Sawarkar, Ritwick, Scherz‐Shouval, Ruth, Denzel, Martin S, Saarikangas, Juha
Publicado en EMBO Rep (2018)

Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics

por Denzel, Martin S., Lapierre, Louis R., Mack, Hildegard I.D.
Publicado en Mech Ageing Dev (2018)

The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase.

por Lange, Heike, Mühlenhoff, Ulrich, Denzel, Martin, Kispal, Gyula, Lill, Roland
Publicado en J Biol Chem (2017)

Mutagenesis screen uncovers lifespan extension through integrated stress response inhibition without reduced mRNA translation

por Derisbourg, Maxime J., Wester, Laura E., Baddi, Ruth, Denzel, Martin S.
Publicado en Nat Commun (2021)

Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis

por Ruegenberg, Sabine, Horn, Moritz, Pichlo, Christian, Allmeroth, Kira, Baumann, Ulrich, Denzel, Martin S.
Publicado en Nat Commun (2020)

Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma

por Allmeroth, Kira, Horn, Moritz, Kroef, Virginia, Miethe, Stephan, Müller, Roman-Ulrich, Denzel, Martin S.
Publicado en Leukemia (2020)

Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1

por Ruegenberg, Sabine, Mayr, Felix A. M. C., Atanassov, Ilian, Baumann, Ulrich, Denzel, Martin S.
Publicado en Nat Commun (2021)

Adiponectin-deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer

por Denzel, Martin S., Hebbard, Lionel W., Shostak, Gregory, Shapiro, Lawrence, Cardiff, Robert D., Ranscht, Barbara
Publicado 2009

T-cadherin is critical for adiponectin-mediated cardioprotection in mice

por Denzel, Martin S., Scimia, Maria-Cecilia, Zumstein, Philine M., Walsh, Kenneth, Ruiz-Lozano, Pilar, Ranscht, Barbara
Publicado 2010

T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion

por Tyrberg, Björn, Miles, Philip, Azizian, Krist T., Denzel, Martin S., Nieves, Maria L., Monosov, Edward Z., Levine, Fred, Ranscht, Barbara
Publicado 2011

Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells

por Horn, Moritz, Kroef, Virginia, Allmeroth, Kira, Schuller, Nicole, Miethe, Stephan, Peifer, Martin, Penninger, Josef M., Elling, Ulrich, Denzel, Martin S.
Publicado en Oncotarget (2018)

T-cadherin Is Essential for Adiponectin-mediated Revascularization

por Parker-Duffen, Jennifer L., Nakamura, Kazuto, Silver, Marcy, Kikuchi, Ryosuke, Tigges, Ulrich, Yoshida, Sumiko, Denzel, Martin S., Ranscht, Barbara, Walsh, Kenneth
Publicado 2013

MULTIVALENT PROTEOGLYCAN MODULATION OF FGF MITOGENIC RESPONSES IN PERIVASCULAR CELLS

por Cattaruzza, Sabrina, Ozerdem, Ugur, Denzel, Martin, Ranscht, Barbara, Bulian, Pietro, Cavallaro, Ugo, Zanocco, Daniela, Colombatti, Alfonso, Stallcup, William B., Perris, Roberto
Publicado 2012

Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response

por Horn, Moritz, Denzel, Sarah I., Srinivasan, Balaji, Allmeroth, Kira, Schiffer, Isabelle, Karthikaisamy, Vignesh, Miethe, Stephan, Breuer, Peter, Antebi, Adam, Denzel, Martin S.
Publicado en iScience (2020)

Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer

por Pichlo, Christian, Toelzer, Christine, Chojnacki, Konrad, Öcal, Sinan, Uthoff, Matthias, Ruegenberg, Sabine, Hermanns, Thomas, Schacherl, Magdalena, Denzel, Martin S., Hofmann, Kay, Niefind, Karsten, Baumann, Ulrich
Publicado en Acta Crystallogr F Struct Biol Commun (2018)

miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging

por Schiffer, Isabelle, Gerisch, Birgit, Kawamura, Kazuto, Laboy, Raymond, Hewitt, Jennifer, Denzel, Martin Sebastian, Mori, Marcelo A, Vanapalli, Siva, Shen, Yidong, Symmons, Orsolya, Antebi, Adam
Publicado en eLife (2021)

Adiponectin attenuates LPS-induced acute lung injury through suppression of endothelial cell activation()

por Konter, Jason M, Parker, Jennifer L, Baez, Elizabeth, Li, Stephanie Z, Ranscht, Barbara, Denzel, Martin, Little, Frederic F, Nakamura, Kazuto, Ouchi, Noriyuki, Fine, Alan, Walsh, Kenneth, Summer, Ross S
Publicado 2011

Oral Supplementation of Glucosamine Fails to Alleviate Acute Kidney Injury in Renal Ischemia-Reperfusion Damage

por Johnsen, Marc, Späth, Martin Richard, Denzel, Martin S., Göbel, Heike, Kubacki, Torsten, Hoyer, Karla Johanna Ruth, Hinze, Yvonne, Benzing, Thomas, Schermer, Bernhard, Antebi, Adam, Burst, Volker, Müller, Roman-Ulrich
Publicado en PLoS One (2016)

N1-acetylspermidine is a determinant of hair follicle stem cell fate

por Allmeroth, Kira, Kim, Christine S., Annibal, Andrea, Pouikli, Andromachi, Koester, Janis, Derisbourg, Maxime J., Andrés Chacón-Martínez, Carlos, Latza, Christian, Antebi, Adam, Tessarz, Peter, Wickström, Sara A., Denzel, Martin S.
Publicado en J Cell Sci (2021)