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Antimalarial Trioxolanes with Superior Drug-Like Properties and In vivo Efficacy
The emergence of artemisinin resistance, combined with certain sub-optimal properties of ozonide agents arterolane and artefenomel has necessitated the search for new drug candidates in the endoperoxide class. Our group has focused on trioxolane analogs with substitution patterns not previously expl...
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| Publicado en: | ACS Infect Dis |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7363035/ https://ncbi.nlm.nih.gov/pubmed/32369341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00064 |
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