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Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene

Majority of cocaine users also consume alcohol. Concurrent use of cocaine and alcohol produces pharmacologically active metabolites cocaethylene and norcocaethylene, in addition to norcocaine. Both cocaethylene and norcocaethylene are more toxic than cocaine itself. Hence, a truly valuable cocaine-m...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Zheng, Xirong, Chen, Xiabin, Zhang, Ting, Zhan, Max, Zhan, Chang-Guo, Zheng, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362898/
https://ncbi.nlm.nih.gov/pubmed/32101217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob02762a
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