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Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene

Majority of cocaine users also consume alcohol. Concurrent use of cocaine and alcohol produces pharmacologically active metabolites cocaethylene and norcocaethylene, in addition to norcocaine. Both cocaethylene and norcocaethylene are more toxic than cocaine itself. Hence, a truly valuable cocaine-m...

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Bibliografiske detaljer
Udgivet i:Org Biomol Chem
Main Authors: Zheng, Xirong, Chen, Xiabin, Zhang, Ting, Zhan, Max, Zhan, Chang-Guo, Zheng, Fang
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362898/
https://ncbi.nlm.nih.gov/pubmed/32101217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob02762a
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