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CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma

Cancer cells commonly develop resistance to immunotherapy by loss of antigen expression. Combinatorial treatments that increase levels of the target antigen on the surface of cancer cells have the potential to restore efficacy to immunotherapy. Here, we use our CRISPR interference– and CRISPR activa...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Ramkumar, Poornima, Abarientos, Anthony B., Tian, Ruilin, Seyler, Meghan, Leong, Jaime T., Chen, Merissa, Choudhry, Priya, Hechler, Torsten, Shah, Nina, Wong, Sandy W., Martin, Thomas G., Wolf, Jeffrey L., Roybal, Kole T., Pahl, Andreas, Taunton, Jack, Wiita, Arun P., Kampmann, Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362346/
https://ncbi.nlm.nih.gov/pubmed/32589729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001346
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