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A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling
G protein-coupled receptors (GPCRs) allow cells to respond to chemical and sensory stimuli through generation of second messengers, such as cyclic AMP (cAMP), which in turn mediate a myriad of processes, including cell survival, proliferation, and differentiation. In order to gain deeper insights in...
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| Publicat a: | PLoS Genet |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7588078/ https://ncbi.nlm.nih.gov/pubmed/33052901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009103 |
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