CRISPR-based genetic interaction maps inform therapeutic strategies in cancer

le Ramkumar, Poornima, Kampmann, Martin
Foilsithe in Transl Cancer Res (2018)

JNK-associated Leucine Zipper Protein Functions as a Docking Platform for Polo-like Kinase 1 and Regulation of the Associating Transcription Factor Forkhead Box Protein K1

le Ramkumar, Poornima, Lee, Clement M., Moradian, Annie, Sweredoski, Michael J., Hess, Sonja, Sharrocks, Andrew D., Haines, Dale S., Reddy, E. Premkumar
Foilsithe in J Biol Chem (2015)

CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma

le Ramkumar, Poornima, Abarientos, Anthony B., Tian, Ruilin, Seyler, Meghan, Leong, Jaime T., Chen, Merissa, Choudhry, Priya, Hechler, Torsten, Shah, Nina, Wong, Sandy W., Martin, Thomas G., Wolf, Jeffrey L., Roybal, Kole T., Pahl, Andreas, Taunton, Jack, Wiita, Arun P., Kampmann, Martin
Foilsithe in Blood Adv (2020)

Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2)

le Reddy, M. V. Ramana, Akula, Balireddy, Jatiani, Shashidhar, Vasquez-Del Carpio, Rodrigo, Billa, Vinay K., Mallireddigari, Muralidhar R., Cosenza, Stephen C., Subbaiah, D. R. C. Venkata, Bharathi, E. Vijaya, Pallela, Venkat R., Ramkumar, Poornima, Jain, Rinku, Aggarwal, Aneel K., Reddy, E. Premkumar
Foilsithe in Bioorg Med Chem (2015)