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T-Cell Receptor CDR3 Loop Conformations in Solution Shift the Relative Vα-Vβ Domain Distributions

T-cell receptors are an important part in the adaptive immune system as they are responsible for detecting foreign proteins presented by the major histocompatibility complex (MHC). The affinity is predominantly determined by structure and sequence of the complementarity determining regions (CDRs), o...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Fernández-Quintero, Monica L., Pomarici, Nancy D., Loeffler, Johannes R., Seidler, Clarissa A., Liedl, Klaus R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360859/
https://ncbi.nlm.nih.gov/pubmed/32733478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01440
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