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Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures
In the past decade, the relevance of antibodies as therapeutics has increased substantially. Therefore, structural and functional characterization, in particular of the complementarity-determining regions (CDRs), is crucial to the design and engineering of antibodies with unique binding properties....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis Group
2020-01-01
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| Colecção: | mAbs |
| Assuntos: | |
| Acesso em linha: | https://www.tandfonline.com/doi/10.1080/19420862.2020.1744328 |
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