Mesocortical BDNF signaling mediates antidepressive-like effects of lithium

Lithium has been used to treat major depressive disorder, yet the neural circuit mechanisms underlying this therapeutic effect remain unknown. Here, we demonstrated that the ventral tegmental area (VTA) dopamine (DA) neurons that project to the medial prefrontal cortex (mPFC), but not to nucleus acc...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Liu, Di, Tang, Qian-Qian, Wang, Di, Song, Su-Pei, Yang, Xiao-Na, Hu, Su-Wan, Wang, Zhi-Yong, Xu, Zheng, Liu, He, Yang, Jun-Xia, Montgomery, Sarah E., Zhang, Hongxing, Han, Ming-Hu, Ding, Hai-Lei, Cao, Jun-Li
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360776/
https://ncbi.nlm.nih.gov/pubmed/32428928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0713-0
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