Mesocortical BDNF signaling mediates antidepressive-like effects of lithium

Lithium has been used to treat major depressive disorder, yet the neural circuit mechanisms underlying this therapeutic effect remain unknown. Here, we demonstrated that the ventral tegmental area (VTA) dopamine (DA) neurons that project to the medial prefrontal cortex (mPFC), but not to nucleus acc...

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Pubblicato in:Neuropsychopharmacology
Autori principali: Liu, Di, Tang, Qian-Qian, Wang, Di, Song, Su-Pei, Yang, Xiao-Na, Hu, Su-Wan, Wang, Zhi-Yong, Xu, Zheng, Liu, He, Yang, Jun-Xia, Montgomery, Sarah E., Zhang, Hongxing, Han, Ming-Hu, Ding, Hai-Lei, Cao, Jun-Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360776/
https://ncbi.nlm.nih.gov/pubmed/32428928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0713-0
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