NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90

Cell migration plays pivotal roles in many biological processes; however, its underlying mechanism remains unclear. Here, we find that NudC-like protein 2 (NudCL2), a cochaperone of heat shock protein 90 (Hsp90), modulates cell migration by stabilizing both myosin-9 and lissencephaly protein 1 (LIS1...

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Vydáno v:Cell Death Dis
Hlavní autoři: Chen, Wenwen, Wang, Wei, Sun, Xiaoxia, Xie, Shanshan, Xu, Xiaoyang, Liu, Min, Yang, Chunxia, Li, Min, Zhang, Wen, Liu, Wei, Wang, Liangjing, Zhou, Tianhua, Yang, Yuehong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360774/
https://ncbi.nlm.nih.gov/pubmed/32665550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02739-9
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