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The L279P Mutation of Nuclear Distribution Gene C (NudC) Influences Its Chaperone Activity and Lissencephaly Protein 1 (LIS1) Stability

LIS1, a gene mutated in classical lissencephaly, plays essential roles in cytoplasmic dynein regulation, mitosis and cell migration. However, the regulation of LIS1 (lissencephaly protein 1) protein remains largely unknown. Genetic studies in Aspergillus nidulans have uncovered that the Nud (nuclear...

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Hlavní autoři: Zhu, Xiao-Jing, Liu, Xunyan, Jin, Qi, Cai, Yuqi, Yang, Yuehong, Zhou, Tianhua
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943274/
https://ncbi.nlm.nih.gov/pubmed/20675372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105494
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